LibGuides: Medicinal Chemistry I: Course Outline (P-I)

Course Outline

Antibiotics

Penicillin
Cephalosporines
Tetracycline
Macroloids
Amino glycosides
Quinolones
Chemistry and synthesis of semisynthetic antibiotics
Biosynthesis structure activity relationship
Historical background
Chemical classification
Nomenclature
Stereochemistry production
Mechanism of action & resistance

Steroids/ terpenoids

Steroid numbering nomenclature stereochemistry
Chemistry & biosynthesis of terpenoids and steroids
Citral
Menthol
Camphor
Serotonin
Artemisinen
Taxol
Teroidal hormones
Sex hormones
Contraceptive agents
Androgens
Adrenal cortex hormones
Cardiovascular drugs and steroids hormone receptors
Digoxin etc

Alkaloidal drugs

Structure
Nomenclature
Tereochemistry
Chemistry
General reactions
Biosynthesis
Mechanism of drug action etc
Ephedrine
Amphetamines
Hyocyamines
Cocaine
Morphine
Codeine
Heroin
Papaverine
Vincristine
Vinblastine
Reserpine
Lysergic acid diethy l amides (LSD)
Quinine
Quinidine (antimalarials)

Phenolic drugs

Cinnamic acid
Coumarins
Flavones X
anthones
Tetrahydro cannibol and related compounds

Oils or fats

History
discovery
biosynthesis
mechanism of drug action
cox-2 inhibitors and receptors
Eicosanoids in clinical development for treatment
Eicosanoids prostaglandins
thromboxanes and leukotrienes

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Relevant Books

Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry by John Block (Editor)
Call Number: 615.19 VLI
ISBN: 0781734819
Publication Date: 2003

E-Books

Methods and Principles in Medicinal Chemistry : Data Mining in Drug Discovery
Author: Hoffmann , Ré my D. Gohier, Arnaud Pospisil, Pavel
Publisher: Wiley-VCH
Date Published: 2013
Frontiers in Medicinal Chemistry, Volume 2
Author: ur-Rahman, Atta- Reitz, Allen B. Choudhary, M. Iqbal
Publisher: Bentham Science Publishers
Date Published: 2010
Frontiers in Medicinal Chemistry, Volume 5
Author: ur-Rahman, Atta- Reitz, Allen B. Choudhary, M. Iqbal
Publisher: Bentham Science Publishers
Date Published: 2010
Methods and Principles in Medicinal Chemistry : Drug Metabolism Prediction
Author: Kirchmair, Johannes Mannhold, Raimund Kubinyi, Hugo
Publisher: Wiley-VCH
Date Published:2014
Frontiers in Medicinal Chemistry, Volume 4
Author: ur-Rahman, Atta- Reitz, Allen B. Choudhary, M. Iqbal Publisher: Bentham Science Publishers Date Published: 2010
Methods and Principles in Medicinal Chemistry : Scaffold Hopping in Medicinal Chemistry
Author: Brown, Nathan Mannhold, Raimund Kubinyi, Hugo
Publisher: John Wiley & Sons
Date Published: 2013
Guide to Reference in Medicine and Health
Author: Modschiedler, Christa Beaubien Bennett, Denise
Publisher: American Library Association
Date Published: 2014
Organic Polymer Chemistry
Author: Singh, Jagdamba Dubey.
Publisher: Pragati Prakashan
Date Published: 2009
Reviews in Computational Chemistry : Reviews in Computational Chemistry
Author: Lipkowitz
Publisher: Wiley-VCH
Date Published: 2007
Clinical Chemistry Research
Author: Mitchem, Brian H. Sharnham, Charles L.
Publisher: Nova
Date Published: 2009
Pharmaceutical Chemistry Organic
Author: Chatwal, G.R. Arora, M.
Publisher: Himalaya Publishing House
Date Published: 2008

E-Books

Medicinal Chemistry
Author: Chatwal, G.R.
Publisher: Himalaya Publishing House
Date Published: 2010
Medicinal Chemistry
Author: Kar, Ashutosh
Publisher: New Age International
Date Published: 2007
Medicinal Chemistry Self Assessment
Author: Zavod, Robin Harrold, Marc
Publisher: ASHP
Date Published: 2014
Advanced Practical Medicinal Chemistry
Author: Kar, Ashutosh
Publisher: New Age International
Date Published: 2004
Medicinal Chemistry Research Progress
Author: Colombo, Giulia P. Ricci.
Publisher: Nova
Date Published: 2009
New Developments in Medicinal Chemistry
Author: Ortega, Marta P. Gil.
Publisher: Nova
Date Published: 2009
Green Techniques for Organic Synthesis and Medicinal Chemistry
Author: Zhang, Wei Cue, Berkeley
Publisher: John Wiley & Sons
Date Published: 2012
Methods and Principles in Medicinal Chemistry : Bioisosteres in Medicinal Chemistry
Author: Brown, Nathan Mannhold, Raimund Kubinyi, Hugo
Publisher: Wiley-VCH
Date Published: 2012
Methods and Principles in Medicinal Chemistry : Microwaves in Organic and Medicinal Chemistry,
Author: Kappe, C. Oliver Stadler, Alexander Dallinger, Doris
Publisher: Wiley-VCH
Date Published: 2013
Methods and Principles in Medicinal Chemistry : Protein-Ligand Interactions
Author: Gohlke, Holger Mannhold, Raimund Kubinyi, Hugo
Publisher: Wiley-VCH
Date Published: 2012
Methods and Principles in Medicinal Chemistry : Drug-Membrane Interactions : Analysis, Drug Distribution, Modeling
Author: Seydel, Joachim K. Wiese, Michael Mannhold, Raimund
Publisher: Wiley-VCH
Date Published:2009
Methods and Principles in Medicinal Chemistry : Pharmacokinetics and Metabolism in Drug Design (3rd Edition)
Design (3rd Edition)
Author: Smith, Douglas A. Allerton, Charlotte Kalgutkar, Amit S.
Publisher: John Wiley & Sons
Date Published: 2012
Uses of Inorganic Chemistry in Medicine
Author: Farrell, Nicholas P McNeill, J H Thompson, Katherine H
Publisher: Royal Society of Chemistry
Date Published: 2007