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Medical Virology: Course content (MLMV-513)

Course description

Introduction

  • Viruses are Distinct from Living Organisms
  • The History of Virology
  • Living Host Systems
  • Structure Size & Shape, Viral Nucleic Acid,
  • Viral Capsid & Symmetry, Viral Protein, Viral Envelope,
  • Atypical virus like Agent

Replication

  • Viral Growth curve
  • Specific event duing growth cycle
  • Attachment , penetration & Uncoating
  • Gene expression and Genome Replication
  • Assembly and release
  • Lysogeny

Genetics & Gene Therapy

Classification of Medically Important Viruses

Pathogenesis

  • The infected cell
  • The infected patient’s
  • Pathogenesis

Host Defenses

  • Nonspecific defenses
  • Specific defenses

Antiviral Drugs

  • Inhibition of early events
  • Inhibition of viral nucleic acid synthesis
  • Inhibit of retroviruses
  • Inhibit of other virsuses
  • Inhition of integrase
  • Inhibition of viral protirn
  • Inhibition of relase of virus
  • Chemoprophylaxis

Viral Vaccines

  • Active immunity
  • Passive immunity
  • Hero immunity

DNA Enveloped Viruses

  • Herpesviruses
  • VarIcella –Zoster Virus (VZV)
  • Cytomegalovirus (CMV)
  • EPSTIN-bar VIRUS (EBV)
  • Poxviruses
  • Smallpox Viruses
  • Molluscum Contagiousum virus

Hepatitis B Viruses

Course description

DNA Nonenveloped Viruses

  • Adenoviruses
  • Papillomaviruses
  • Parvoviruses B-19

RNA Enveloped Viruses

  • Orthomyxoviruses
  • Paramyxoviruses
  • Coronaviruses
  • Togaviruses
  • Rhabdoviruses
  • Retroviruses
  • Respiratory viruses
  • Measles,mumps,Rubella viruses
  • Rabies viruses
  • Hepatitis C Virsues
  • Human T cell lymphotrophic virus
  • Human Immunodeficiency Virus

RNA Nonenveloped Viruses

  • Picornaviruses
  • Coxackieviruses
  • Echoviruses
  • Calciviruses
  • reoviruses
  • Enteroviruses
  • Rhinoviruses
  • Reoviruses (Rotaviruses)
  • Hepatitis A virus

Hepatitis Viruses

  • Hep A. Hep B. Hep C. Hep D

Arboviruses

Tumor Viruses

  • Over view,Malignant Tranformation of Cells
  • Provirus & oncogenes, outcome of tumor virus infection
  • Tramsmission of tumor virus
  • Evidence for human tumor virusrs
  • Human pappiloma viruses
  • Epstin bar virus
  • Hep B virus. Hcv virus, human herpesvirus B
  • Vaccine against Cancer
  • Animal tumor virus
  • DNA tumor virus
  • Rna tumor virus

Hepatitis viruse

    • Slow Viruses & Prions
    • Human Immunodeficiency Virus

Course description

Minor Viral Pathogens

  • Astroviruses
  • Chikungunya virus
  • Hantaviruses
  • Ebola viruses
  • Hendra Virus
  • Herps B Virus
  • Human Herpevirus 6
  • Human Metapneumoviruses
  • Japanese enchphalitis virus
  • Lessa fever virus
  • Lypmhtoic chorimeniningitis
  • Marburg virus
  • Nipah virus
  • Poxviruses of animal origin
  • spumaviruses

Genomes without Viruses, Viruses without Genomes

  • Satellites and Viroids
  • Prions

Practical

  • Identification of cell culture
  • Complement fixation
  • Hemagglutination inhibition
  • Neutralization
  • Fluorescent –Antibody Assay
  • Radioimmunoassay
  • ELISA
  • Immunoelectron microscopy
  • Serological procedure
  • Detection of viral Antigen
  • Detection of viral nucleic Acid

Reference books