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Advances in Molecular Genetics (BIO-702) MPhil : Course Outline

The course is designed to cover a broad array of topics mainly in eukaryotic Genetics, including gene structure, genetic and genomic analysis, gene expression and regulation, the students will understand the transmission genetics of prokaryotes and eukary

Course Description

The course is designed to cover a broad array of topics mainly in eukaryotic Genetics, including gene structure, genetic and genomic analysis, gene expression and regulation, the students will understand the transmission genetics of prokaryotes and eukaryotes, developmental and non-chromosomal genetics, including mapping and identification of disease genes, and gene therapy

Course Outline

COURSE OBJECTIVES

This course will provide:

  • To provide a deep insight about the recent advances in molecular genetics
  • To understand mechanisms underlying different genetic disorders

COURSE CONTENT

  • Genes in Pedigrees
  • Organization of the human genome: 
  • The limited autonomy of the mitochondrial genome
  • Human gene Expression
  • Pseudogenes and genes fragments
  • Transposition through an RNA intermediate. 
  • Human Genome Expression
  • Instability of the human genome: mutations
  • Physical and transcript mapping: the importance of sequence tagged sites
  • Identifying human and animal disease genes
  • Molecular pathology
  • Genetic testing in individuals and population
  • Cancer Genetics
  • Complex Disease theories and results
  • Genetic manipulation of animals
  • General gene therapy strategies
  • Treatment using conventional animals or human products.