COURSE CONTENTS CELL
• Introduction to Biochemistry
• Cell: (Biochemical Aspects)
• Cell Membrane Structure
• Membrane Proteins
• Receptors & Signal Molecules
BODY FLUIDS
• Structure and properties of Water
• Weak Acids & Bases
• Concept of pH &pK
• Buffers, their mechanism of action
• Body buffers
BIOMOLECULES AMINO ACIDS, PEPTIDES & PROTEINS
• Amino acids: Classification
• Acid-Base Properties
• Functions & Significance
• Protein Structure, Primary, Secondary & Super secondary. &, Structural Motifs
• Tertiary & Quaternary Structures of Proteins
• Protein Domains
• Classification of Proteins
• Fibrous proteins (collagens and elastins ) & Globular proteins
ENZYMES
• Introduction
• Classification & Properties of Enzymes
• Coenzymes
• Isozymes & Proenzymes
• Regulation & Inhibition of Enzyme activity & enzymes inhibitors
• Clinical Diagnostic Enzymology
CARBOHYDRATES
• Definition
• Classification•
Biochemical Functions & Significance of Carbohydrates
• Structure & Properties of Monosaccharides& Oligosaccharides
• Structure & Properties of Polysaccharides
• Bacterial cell Wall
• Heteropolysaccharides
• GAGS
LIPIDS
• Classification of Lipids
• Fatty Acids: Chemistry
• Classification occurrence & Functions
• Structure & Properties of Triacylglycerols and Complex Lipids
• Classification & Functions of Eicosanoids
• Cholesterol: Chemistry, Functions & Clinical Significance
• Bile acids/salts.
NUCLEIC ACIDS
• Structure, Functions & Biochemical Role of Nucleotides
• Structure & Functions of DNA
• Structure & Functions of RNA.
NUTRITIONAL BIOCHEMISTRY MINERALS & TRACE ELEMENTS
• Sources
• RDA
• Biochemical Functions & Clinical Significance of Calcium & Phosphorus
• Sources
• RDA
• Biochemical Functions & Clinical Significance of Sodium Potassium& Chloride
• Metabolism of Iron, Cu, Zn, Mg, Mn, Se, I,F.
VITAMINS
• Sources
• RDA
• Biochemical Functions & Clinical Significance of Fat Soluble Vitamins.
NUTRITION
• Dietary Importance of Carbohydrates, Lipids & Proteins
• Balanced Diet