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Introductory Biochemistry - (IBCL-601) (HND): Course Content

Introductory biochemistry is the study of chemical processes within and relating to living organisms. It combines chemistry and biology to understand the chemical basis of life, focusing on the structure, function, and interactions of biomolecules like pr

Course Outline

Introduction, scope and importance of biochemistry;
Brief introduction of prokaryotic and eukaryotic cells;
Bio-macromolecules: composition and organization;
Energy and Principles of bioenergetics;
Water: Properties of water, acid/base properties, dissociation of water and pH value, pH buffering capacity, transportation mechanisms across bio-membranes and osmosis,
Proteins: Amino acids - structure, nomenclature, classification, Primary structure of proteins - peptide bond, sequencing, synthesis, Secondary structure - α-helices, β-sheets, Three dimensional structure of proteins, methods for protein structural determination - Xray, NMR and homology modeling, tertiary and quaternary structures of proteins, protein denaturation, Methods for purifying and studying proteins; Enzymes: functions, mode of action, specificity and inhibition, classification and nomenclature, factors affecting enzymes activity,
Introduction to carbohydrates (Glycobiology): biosynthesis, metabolism, glycolysis, Kerbs cycle, Mitochondrial electron transport chain and ATP synthesis;
Lipids: introduction, lipogenesis, lipids and lipoproteins in relation to lipid storage
diseases, sterol and steroids; Overview of nucleic acids

Course Description and Learning Outcomes

Course Description:
This introductory biochemistry course explores the molecular foundations of living organisms,
focusing on the structure and function of proteins, nucleic acids, lipids, and carbohydrates.
Students will examine key biochemical pathways and their roles in metabolism, while developing
a foundational understanding of how biochemical principles apply to health and disease. Emphasis
is placed on critical thinking and problem-solving through practical laboratory exercises and
theoretical discussions.
Learning Outcomes:
Acquaint knowledge about the nomenclature, structures and properties of chemical constituents
Grasp the knowledge about the energy yielding cycle like glycolysis, Kerb’s cycle, β- oxidation etc.

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