Pharmacology: Course Outline
- Definition & Branches/divisions of pharmacology, objectives of learning pharmacology.
- Definition of drug, drug nomenclature & sources of drugs.
- Standard sources of drug information, Pharmacopoeas and Formularies (only relevant information)
- Dosage forms and doses of drugs.
- Pharmacokinetics: basic principles and their clinical application
- Route of drug administration.
- Transport of drugs across cell membranes
- Absorption of drugs and bioavailability
- Drug reservoirs, distribution and redistribution of drugs, plasma protein binding and volume of distribution.
- Bio-transformation of drugs.
- Excretion of drug, enterohepatic recirculation, plasma half-life,clearance
- Mechanism of drug action.
- Receptors and post receptor molecular mechanism of drug action
- Mechanism of drug action other than mediated through drug receptors.
- Dose response curves, structure-activity relationship.
- Factors modifying action and doses of drugs.
- Adverse drug reactions & drug toxicity/poisoning
- Drug Interactions
Locally Acting Drugs (definitions with examples)
- Dermatological and topical drugs
- Demulcents, emollients, irritants, counter irritants, astringents.
- Antiseborrhoeics, locally acting enzymes.
- Antiseptics and disinfectants.
- Histamine & antihistamines
- Introduction to other Mediators: