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Molecular Pharmacology: Course Outline (401)

The Molecular Pharmacology Graduate Program offers didactic and research training in most of the fundamental aspects of this discipline. The course work in the program will educate students in the key principles of the discipline of pharmacology.

Course Outline

Pharmacology of cell signaling

  • Introduction and scope
  • Cell structure and function
  • Signal transduction
  • Molecular basis of drug receptor interactions
  • Types and classification of receptors
  • Drugs affecting the g protein linked receptor systems
  • Drugs affecting tyrosine kinase linked receptor systems drugs affecting the ion channel functions
  • Drugs affecting the nuclear receptor signaling

Pharmacology of gene expression

  • Drugs affecting gene expression and regulation
  • Transcription
  • RNA processing
  • Translation
  • Post translational modifications
  • DNA and RNA synthesis inhibitors
  • Protein synthesis and secretion inhibitors

Pharmacology of cellular interactions

  • Drugs affecting cell-cell interactions
  • Matrix metalloprotease inhibitors
  • Cell cycle and drugs acting on the cell cycle

Molecular therapeutics

  • DNA and RNA as drugs
  • Pharmacogenomics
  • Pharmacogenetics
  • Gene therapy
  • Protein and peptide biological drugs
  • Stem cell therapy
  • Molecular approach to drug design