Applications of polymers in Pharmacy: Course Outline (908)
Course Outline
Classification
Synthesis
Reactions
Crystallinity
Polymer degradation mechanism
Copolymerization and their applications in Pharmacy
Thermoplastic and thermosetting polymers
Natural polymers
Non-biodegradable polymers and biodegradable polymers
Mucoadhesive polymers polymer–supported reactions versus solution-phase reactions
Automated synthesis the breakthrough point
Synthesis of polypeptides polynucleotide
Combinatorial chemistryprincipals
Methods
Drug design and methodology
Polymers in controlled drug delivery
Introduction to synthetic polymers
Conventional vs controlled release
Advantages and disadvantages
Pharmacokinetic consideration
Polymer as drug carrier
Monolithic matrix controlled systems drug dissolution/diffusion controlled system constant activity reservoir
Unsteady state analysis (time-lag and burst effect)
Drug release from multilayer membrane devices
Drug release from matrix system swelling controlled systems hydrogels
Polymer degradation and erosion
Erosion/drug diffusion controlled swelling/erosion controlled
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