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General Pharmacology: Course Outline (919)

This course covers selected topics in pharmacology pertaining to the nervous, cardiovascular, endocrine, and metabolic systems. Pathologies of the various systems and the mechanisms of pharmacological intervention will be covered.

Course Outline

Introduction to pharmacology

Sources of drugs

Dosage forms and doses of drugs

Drug administration

Absorption of drugs and processes involved in drug absorption

Factors modifying absorption of drugs

Transport of drugs across cell-membrane

Distribution of drugs

Plasma protein binding

Bioavailability

Biotransformation of drugs

Enzyme induction

Enzyme inhibition and entero-hepatic circulation

Plasma half- life of drugs

Its clinical importance

Dose response curves

Excretion of drugs

Drug receptors

Structure- activity relationship

Receptors for physiological regulatory molecules

Factors modifying actions of drugs

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