Basic Hematology: Course Outline

Blood (Cell, plasma, serum) 

• Introduction to Haematology 
• Haematopoiesis (erythropoiesis, leucopoiesis, thrombopoiesis)  

Pathophysiology of the following: Anaemias

• Iron deficiency anaemia 
• Megaloblastic anaemia 
• Aplastic anaemia 
• Thalassemia major 
• Sideroblastic anaemia 
• Anaemia of chronic disorder

Leukemias 

• Acute Lymphoblastic leukaemia 
• Acute Myeloblastic leukaemia 
• Chronic Myeloid leukaemia 
• Chronic lymphocytic leukaemia

Lymphomas 

• Hodghkins lymphoma 
• Non Hodghkins lymphoma

Plasma cell disorders 

• Multiple Myeloma

Haemostasis 

• Normal Hemostasis 
• Hereditary Coagulation Disorders

- Hemophilia A

- Hemophilia B 

• Acquired Coagulation Disorders

- Vitamin K Deficiency

- Haemorrhagic disease of the newborn

- Liver Disease

- Disseminated intravascular Coagulation

Thrombosis

- Venous Thrombosis

- Arterial Thrombosis

Hematology is the study of blood and the disorders related to it. Human blood consists of blood cells and plasma. Blood has many functions, including transporting oxygen and nutrients to tissues, removing waste materials (e.g., carbon dioxide, urea), regulating body temperature, and carrying cells responsible for coagulation and immune response.

Practical:

Students should be able to: 

• Prepare and use common anticoagulants 
• Operate fully Automated Haematology Analyzer 
• Preparation and staining of blood films 
• Reticulocyte staining and reticulocyte count 
• Bone marrow aspiration and trephine biopsy 
• Cytochemical stains 
• Haemoglobin studies 
• Screening tests for G6PD deficiency 
• Sickling test 
• Coagulation studies 
• Platelet function studies 
• Thrombophilia screening 
• Cellulose Acetate Membrane Electrophoresis 
• Quality control in routine haematology