General Pathology: Course Outline (BSGP613)

LEARNING OBJECTIVES:
Describe the responses to different types of injury at the cellular and subcellular level
• Enlist the differences between necrosis and apoptosis
• Describe different morphological patterns of tissue necrosis
• Describe the different types of responses of the cells to stress
• Describe the different types of exogenous and endogenous pigmentations
• Describe the sequence of vascular changes in acute inflammation (vasodilation,
increased permeability) and their purpose
• Describe the steps involved in phagocytosis and the role of IgG and C3b as
opsonin and receptors
• Compare and contrast acute vs chronic inflammation with respect to causes,
nature of the inflammatory response, and tissue changes10. Describe the
differences between the various cell types (i.e., labile, stable, and permanent cells)
in terms of their regeneration potential. List examples of each cell type
• Distinguish between fibrinous, purulent, and serous inflammation. Define an
abscess.
• Describe the systemic manifestations of inflammation and their general
physiology, including fever, leukocyte left shift, and acute phase reactants
• Define and understand the process of excessive growth of different types of cell

1. Pathology – Definition, various fields of pathology, importance and uses of
pathology and its various subspecialties
2. Inflammation - Pathogenesis and significance
3. Causes of inflammation 

4. Acute inflammation - Cardinal signs, gross and histologic appearance, possible
outcomes
5. Healing- definition, significance and factors responsible
6. Regeneration - definition, significance, ongoing scientific research
7. Edema- definition, types and causes
8. Embolism- definition, causes and effect on tissue
9. Shock - Causes, Types, Effects on human body, Clinical sign and symptoms,
Basic principles of management
10. Adaptive Structural Changes: Types and causes of adaptation
11. Hyperplasia- definition, causes, types and examples
12. Metaplasia- definition, pathogenesis and significance
13. Anaplasia- definition
14. Genetics - Important function of genes, Mutation and its causes
15. Metabolic Disorders
16. Cell injury - Pathogenesis and etiology of cell injury, Reversible and irreversible
cell injury, Possible outcomes of cell injury
17. Three lines of defense in human body
18. Chronic inflammation - Gross and histologic appearance, possible outcomes,
Comparison
19. Scarring- definition, significance and factors responsible
20. Ischemia- definition, causes and effect on tissue
21. Thrombosis- definition, causes and effect on tissue
22. Infarction- definition, causes and effect on tissue
23. Cell death: Necrosis and apoptosis- description and differentiating points
24. Hypertrophy- definition, causes, types and examples
25. Atrophy- definition and cause and examples
26. Dysplasia- definition, pathogenesis and significance
27. Neoplasia: pathogenesis, Types with examples - benign and malignant
28. Overview of common genetic disorders and role of counseling
29. Disorders of Circulation

Robbins Basic Pathology by Vinay Kumar; Abul K. Abbas; Jon C. Aster

Call Number: 616.07 KUM

ISBN: 9781437717815

Publication Date: 2012