General Pathology: Course content (MLGP-513)

1. Cell Injury and adaptation
Cell Injury

• Reversible and Irreversible Injury
• Fatty change, Pigmentation, Pathologic calcification
• Necrosis and Gangrene

Cellular adaptation

• Atrophy, Hypertrophy
• Hyperplasia, Metaplasia, Aplasia

2. Inflammation
Acute inflammation

• vascular changes, Chemotaxis, Opsonization and Phagocytosis
• Enlist the cellular components and chemical mediators of acute inflammation
• Differentiate between exudates and transudate

Chronic inflammation

• Etiological factors, Granuloma

3. Cell repair and wound healing

• Regeneration and Repair
• Healing--- steps of wound healing by first and second intention
• Factors affecting healing
• Enlist the complications of wound healing

1. Cell Injury and adaptation
Cell Injury

• Reversible and Irreversible Injury
• Fatty change, Pigmentation, Pathologic calcification
• Necrosis and Gangrene

Cellular adaptation

• Atrophy, Hypertrophy
• Hyperplasia, Metaplasia, Aplasia

2. Inflammation
Acute inflammation

• vascular changes, Chemotaxis, Opsonization and Phagocytosis
• Enlist the cellular components and chemical mediators of acute inflammation
• Differentiate between exudates and transudate

Chronic inflammation

• Etiological factors, Granuloma

3. Cell repair and wound healing

• Regeneration and Repair
• Healing--- steps of wound healing by first and second intention
• Factors affecting healing
• Enlist the complications of wound healing

Practicals:
1. Adaptive Response
Hyperplasia

• Endometrial Hyperplasia, Gross, Microscopic

2. Acute Inflammation

• Morphological patterns

3. Recognition of Ulcer , Abscess
4. Neoplasia – Gross examination of Cystadenoma ovary (Serous / Mucinous), Teratoma ovary,
Cystadenocarcinoma ovary, Lipoma, Fibroiduterus