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Medicinal Chemistry: Pharmaceutical Chemistry-IVB

Medicinal chemistry is a chemistry-based discipline, also involving aspects of biological, medical and pharmaceutical sciences.

Course Outline

General Properties, Chemistry Biological Action, Structure Activity Relationship And Therapeutic Applications Of The Following:

i. Sulphonamides: Prontosil, sulphanilamide, Sulphapyridine, sulphadimidine, Sulfamethoxazole, Sulfadiazine and Sulfafurazole.

ii. Antimalarials: 4-Aminoquinolines, 8-Aminoquinolines, 9-Amino acridines, Biguanides, Pyrimidine analogues, Mefloquine and Cinchoha alkaloids.

iii. Diuretics: Mercaptomerin, Meralluride, Thiazides, Sprironolac-tone, Theophylline, Furosemide, Acetazolamide, Ethacrynic acid and Triameterene.

iv. Antitubercular Drugs: Ethambutol, Isonicotinic acid, Hydrazid, Rifampacin, Thioguanine, Pyrazinamide, cycloserine, Ethunamide, Cytarabine, 5-Flourouracil and Dacarbazine.

v. Antiviral Drugs: Acyclovir, Tromantadine Hydrochloride and Ribavirin.

vi. Immunosuppressant Agents: Azathioprine and Cyclosporin.

vii. Antibiotics: Penicillins, Cephalosporins, Streptomycin, Chloramphenicol, Tetracyclines, Kanamycin and Erythromycin. 

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