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Pharmacology & Therapeutics-IIB (PHARM 517): Course Outline (Theory & Practical)

Principles to Practice uses pharmacology principles to integrate the most recent advances in basic biomedical sciences into deciding the best medications to treat illness and preserve health.

Course Outline (Theory)


  •  Basic principles of chemotherapy
  •  Antibacterials
    • Folate antagonists
    • Sulphonamides
    • Cell wall synthesis inhibitors
    • Penicillin
    • Cephalosporins
    • Carbapenam
    • Monobactam
    • Protein synthesis inhibitors
    • Aminoglycosides
    • Tetracyclines
    • Chloramphenicol
    • Macrolides
    • Nucleic acid synthesis inhibitors
    • Quinolones and miscellaneous Antibiotics
    • Antimycobacterial drugs
    • Urinary tract antiseptics
  • Anti-fungals:
  • Anti-virals
  • Anti-protozoals anti-malarias, anti-amebiasis, anthelmintics  Anti- leishmanials
  • Anti-neoplastic drugs


  • Pharmacology of immuno-suppressants and stimulants


  • Pollution and its types (water, air, food)
  • Poison and principle of treatment of poisoning.
  • Poisoning
    • (Sign & symptom and treatment):
    • Ethanol
    • Barbiturates
    • Digitalis
    • Salicylates
    • Strychnine
    • Narcotics
    • Nicotine
    • Paracetamol
    • Benzodiazepines and organophosphorous compounds
  • Chelating agents and their role in poisoning: Dimercaprol, Calcium disodium edentate (Calcium EDTA), Pencillamine and Defroxamine.


  • Only an introduction will be given of the banned and obsolete drug products
  • While dealing with Pharmacology stress should be laid to the group actions of related drugs and only important differences should be discussed of the individual drugs placed in same group
  • Newly introduced drugs should be included in the syllabus while drugs with no clinical and therapeutic values ought to be excluded from syllabus at any time
  • The prototype drugs in each group from the latest edition of the recommended books. 

Relevant Books

Course Outline (Practical)

Note:  Practical of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. 

  • To study the convulsant effects of strychnine and picrotoxin in frogs and to determine the site of action
  • To identify the unknown (convulsant) drug and determine its site of action
  • To study the effects of Adrenaline on Human Eyes
  • To study the effects of Pilocarpine on Human Eyes
  • To study the effect of Homatropine on Human Eyes
  • To identify and observe the effects of unknown drugs on Human Eyes
  • To study the effects of local anaesthetic drugs on human and the nerve plexus of frog
  • To identify and differentiate the effects of unknown drug on human and the nerve plexus of frog
  • To demonstrate the effects of Acetylcholine on the Rectus abdominus muscle of frog and competitive pharmacological antagonism by Neuromuscular blocking agent e.g. Gallamine
  • To identify the unknown drug by performing pharmacological competitive antagonism on Rectus abdominus muscle of Frog
  • To study the anti-coagulant effects of Heparin and oral anti-coagulants on Rabbits
  • To identify the unknown anticoagulant drug using Rabbits
  • To demonstrate the Graded Dose-Response curve of Acetylcholine on Rabbit intestine
  • To identify unknown concentration of Acetycholine from Graded Dose-Response curves
  • To demonstrate the general anesthetic effect on rabbits
  • To demonstrate the effect of sedatives and hypnotics on rabbits
  • To demonstrate the anti-nociceptive (analagesic) effect on mice
  • To demonstrate antidepressant effect in rats (forced swimming test, tail suspension test, Yohimbin lethality test)


Relevant Books