Introduction to molecular modeling and drug development
- Terms used
- Brief discussion of in silico drug designing
- Structure based drug designing
- Ligand based drug designing and role of different software in computer aided
- Drug designing
Example of selected drug design
- Discussion and study of drug designing of different drugs including antipsychotic,
- Antidepressants,
- Antiviral and antibacterial drugs
Molecular targets for development of drugs
- Study of molecular targets including DNA
- RNA
- Nucleotides and other enzymes of cell cycle
Introduction to screening methods
- Study and discussion of low through put screening (LTS)
- High through put
- Screening (HTS)
- Virtual screening and other instrumental techniques that are associated with HTS
Analytical methods
- Application of various analytical methods to the assay of antibiotics
- Benzodiazepines
- Phenol thiazines
- Steroids and sulfonamides
Structure properties of macromolecules
- Study and discussion of macromolecules including protein
- Carbohydrate and fat molecule
- Structure and their role in physiological pathways
Concept of bio-selectivity in drug
- Study the selectivity of drug molecule with the target sites
Enzymes
- Study enzymes
- Their function
- Their role and various types of enzymes in the body