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Drug Stability & Drug development: Courser Outline (P1, P-III)

pharmaceutical chemistry is the study and development of new drugs. It involves cures and remedies for diseases, analytical techniques, pharmacology, metabolism, quality assurance, and drug chemistry.

Course Outline

Introduction to molecular modeling and drug development

  • Terms used
  • Brief discussion of in silico drug designing
  • Structure based drug designing
  • Ligand based drug designing and role of different software in computer aided
  • Drug designing

Example of selected drug design

  • Discussion and study of drug designing of different drugs including antipsychotic,
  • Antidepressants,  
  • Antiviral and antibacterial drugs

Molecular targets for development of drugs

  • Study of molecular targets including DNA
  • RNA
  • Nucleotides and other enzymes of cell cycle

Introduction to screening methods

  • Study and discussion of low through put screening (LTS)
  • High through put
  • Screening (HTS) 
  • Virtual screening and other instrumental techniques that are associated with HTS

Analytical methods

  • Application of various analytical methods to the assay of antibiotics
  • Benzodiazepines
  • Phenol thiazines
  • Steroids and sulfonamides

Structure properties of macromolecules

  • Study and discussion of macromolecules including protein 
  • Carbohydrate and fat molecule
  • Structure and their role in physiological pathways

Concept of bio-selectivity in drug

  • Study the selectivity of drug molecule with the target sites


  • Study enzymes
  • Their function
  • Their role and various types of enzymes in the body

Relevant Books