Introduction to medicinal chemistry
- General properties
- Chemistry
- Biological action
Structure activity relationship and therapeutic applications of the following
- Anti-septics
- Sulphonamides
- Antimalarials
- Anthelmintics
- Diuretics
- Anti-tubercular drugs
- Antiviral drugs and immunosuppressant agents
- Alkaloids
- Vitamins
- Hormones
- Anti-neoplastic agents
- Sedatives and hypnotics
- Anesthetics
- Local anesthetics
- General anesthetics
- Analgesics and antipyretics
Cell membrane chemistry
- Receptors
- Drug receptor interaction
- G-protein coupled receptors
- Ion channel linked receptors
- Ligand gated ion channels (LGICs)
Ligand-Receptors theories
- Clarks occupancy theory
- Rate theory
- Induced fit theory
- Macromolecular perturbation theory and activation aggregation theory
Drug design tools
Conventional methods of drug design
- Lead
- Discovery of lead
- Lead optimization
- Objective of lead optimization
- Pharmacophoric identification and analog approach of drug designing
- Prodrug Concept for drug design
- Drug targeting and antibody directed enzyme prodrug therapy (ADEPT)
- Soft drug design
Rational design of enzymes inhibitors
- Design of non-covalently binding enzymes inhibitors:
- Rapid reversible inhibitors
- Slow
- Tight and slow-tight inhibitors
- Transition state analogues
- Multisubstrate inhibitors
- Current developments with respect to the inhibition of the different enzymes
Foye's principles of medicinal chemistry by 
Textbook of inorganic pharmaceutical and medicinal chemistry by 
